Application
Western blot analysis of SCG5 Antibody (C-term) in K562 cell line lysates (35ug/lane). SCG5 (arrow) was detected using the purified Pab.| Product Name | SCG5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SCG5; SGNE1; Neuroendocrine protein 7B2; Pituitary polypeptide; Secretogranin V; Secretogranin-5; Secretory granule endocrine protein I; N-terminal peptide; C-terminal peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SGNE1 |
|---|---|
| Alternative Names | SCG5 SGNE1 Neuroendocrine protein 7B2 Pituitary polypeptide Secretogranin V Secretogranin-5 Secretory granule endocrine protein I N-terminal peptide C-terminal peptide |
| Molecular Weight(MW) | 23730 Da |
| Function | Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro |
| Tissue Specificity | This SCG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183~212 amino acids from the C-terminal region of human SCG5. |
| Cellular Localization | Secreted. Note=Neuroendocrine and endocrine secretory granules |
| Entrez Gene | 6447 |
|---|
Application
Western blot analysis of SCG5 Antibody (C-term) in K562 cell line lysates (35ug/lane). SCG5 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
