Application
SCUBE3 Antibody (Center) western blot analysis in Uterus tissue lysates (35ug/lane).This demonstrates the SCUBE3 antibody detected the SCUBE3 protein (arrow).Application
SCUBE3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the SCUBE3 antibody detected the SCUBE3 protein (arrow).| Product Name | SCUBE3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SCUBE3; CEGF3; Signal peptide, CUB and EGF-like domain-containing protein 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CEGF3 |
|---|---|
| Alternative Names | SCUBE3 CEGF3 Signal peptide CUB and EGF-like domain-containing protein 3 |
| Molecular Weight(MW) | 109282 Da |
| Function | Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression |
| Tissue Specificity | Highly expressed in osteoblasts. In normal lung, mainly expressed in bronchial epithelial cells. Tends to be up-regulated in lung cancer cells |
| Cellular Localization | Secreted. Cell surface. |
| Entrez Gene | 222663 |
|---|---|
| Nucleotide Accession | NP_689966.2 |
Application
SCUBE3 Antibody (Center) western blot analysis in Uterus tissue lysates (35ug/lane).This demonstrates the SCUBE3 antibody detected the SCUBE3 protein (arrow).
Application
SCUBE3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the SCUBE3 antibody detected the SCUBE3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
