Application
SEC14L2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SEC14L2 antibody detected the SEC14L2 protein (arrow).| Product Name | SEC14L2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SEC14L2; C22orf6; KIAA1186; KIAA1658; SEC14-like protein 2; Alpha-tocopherol-associated protein; Squalene transfer protein; Supernatant protein factor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C22orf6 KIAA1186 KIAA1658 |
|---|---|
| Alternative Names | SEC14L2 C22orf6 KIAA1186 KIAA1658 SEC14-like protein 2 Alpha-tocopherol-associated protein Squalene transfer protein Supernatant protein factor |
| Molecular Weight(MW) | 46145 Da |
| Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell |
| Tissue Specificity | Widely expressed. Strong expression in liver, brain and prostate |
| Cellular Localization | Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha- tocopherol |
| Entrez Gene | 23541 |
|---|---|
| Nucleotide Accession | NP_036561.1 NP_203740.1 |
Application
SEC14L2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SEC14L2 antibody detected the SEC14L2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
