Application
SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).Application
SEMA4C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | SEMA4C Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SEMA4C; KIAA1739; SEMAI; Semaphorin-4C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1739 SEMAI |
|---|---|
| Alternative Names | SEMA4C KIAA1739 SEMAI Semaphorin-4C |
| Molecular Weight(MW) | 92623 Da |
| Function | Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248' Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade |
| Tissue Specificity | This SEMA4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 791-821 amino acids from the C-terminal region of human SEMA4C. |
| Cellular Localization | Cell junction, synapse, postsynaptic cell membrane, postsynaptic density; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein (By similarity) |
| Entrez Gene | 54910 |
|---|---|
| Nucleotide Accession | NP_060259.4 |
Application
SEMA4C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SEMA4C antibody detected the SEMA4C protein (arrow).
Application
SEMA4C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
