Application
Western blot analysis of SELS Antibody (Center) in 293 cell line lysates (35ug/lane). SELS (arrow) was detected using the purified Pab.Application
SELS Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | SELS Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VIMP; SELS; Selenoprotein S; VCP-interacting membrane protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SELS |
|---|---|
| Alternative Names | VIMP SELS Selenoprotein S VCP-interacting membrane protein |
| Molecular Weight(MW) | 21163 Da |
| Function | Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination |
| Tissue Specificity | This SELS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44~74 amino acids from the Center region of human SELS. |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm (By similarity) |
| Entrez Gene | 55829 |
|---|
Application
Western blot analysis of SELS Antibody (Center) in 293 cell line lysates (35ug/lane). SELS (arrow) was detected using the purified Pab.
Application
SELS Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
