Application
Western blot analysis of hSENP1-K578 in HL-60, Hela cell line lysates (35ug/lane). SENP1 (arrow) was detected using the purified Pab.| Product Name | SENP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SENP1; Sentrin-specific protease 1; Sentrin/SUMO-specific protease SENP1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SENP1 Sentrin-specific protease 1 Sentrin/SUMO-specific protease SENP1 |
|---|---|
| Molecular Weight(MW) | 73481 Da |
| Function | Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2 Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity |
| Tissue Specificity | Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine |
| Cellular Localization | Nucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus |
| Entrez Gene | 29843 |
|---|
Application
Western blot analysis of hSENP1-K578 in HL-60, Hela cell line lysates (35ug/lane). SENP1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
