Application
SF1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SF1 antibody detected the SF1 protein (arrow).| Product Name | SF1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SF1; ZFM1; ZNF162; Splicing factor 1; Mammalian branch point-binding protein; Transcription factor ZFM1; Zinc finger gene in MEN1 locus; Zinc finger protein 162 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ZFM1 ZNF162 |
|---|---|
| Alternative Names | SF1 ZFM1 ZNF162 Splicing factor 1 Mammalian branch point-binding protein Transcription factor ZFM1 Zinc finger gene in MEN1 locus Zinc finger protein 162 |
| Molecular Weight(MW) | 68330 Da |
| Function | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor |
| Tissue Specificity | Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7536 |
|---|---|
| Nucleotide Accession | NP_001171502.1 NP_001171501.1 NP_973724.1 |
Application
SF1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SF1 antibody detected the SF1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
