Application
SFRP5 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SFRP5 antibody detected the SFRP5 protein (arrow).Application
SFRP5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SFRP5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SFRP5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SFRP5; FRP1B; SARP3; Secreted frizzled-related protein 5; Frizzled-related protein 1b; Secreted apoptosis-related protein 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FRP1B SARP3 |
|---|---|
| Alternative Names | SFRP5 FRP1B SARP3 Secreted frizzled-related protein 5 Frizzled-related protein 1b Secreted apoptosis-related protein 3 |
| Molecular Weight(MW) | 35563 Da |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina |
| Tissue Specificity | Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle |
| Cellular Localization | Secreted (By similarity). |
| Entrez Gene | 6425 |
|---|---|
| Nucleotide Accession | NP_003006.2 |
Application
SFRP5 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SFRP5 antibody detected the SFRP5 protein (arrow).
Application
SFRP5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SFRP5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
