Application
SGPL1 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SGPL1 antibody detected the SGPL1 protein (arrow).Application
SGPL1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGPL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SGPL1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SGPL1; KIAA1252; Sphingosine-1-phosphate lyase 1; Sphingosine-1-phosphate aldolase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1252 |
|---|---|
| Alternative Names | SGPL1 KIAA1252 Sphingosine-1-phosphate lyase 1 Sphingosine-1-phosphate aldolase |
| Molecular Weight(MW) | 63524 Da |
| Function | Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis |
| Tissue Specificity | Found in liver and kidney. |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type III membrane protein |
| Entrez Gene | 8879 |
|---|---|
| Nucleotide Accession | NP_003892.2 |
Application
SGPL1 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SGPL1 antibody detected the SGPL1 protein (arrow).
Application
SGPL1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGPL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
