Application
SH3BP1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SH3BP1 antibody detected the SH3BP1 protein (arrow).| Product Name | SH3BP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SH3BP1; SH3 domain-binding protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SH3BP1 SH3 domain-binding protein 1 |
|---|---|
| Molecular Weight(MW) | 75713 Da |
| Function | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity) |
| Tissue Specificity | This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the Central region of human SH3BP1. |
| Entrez Gene | 23616 |
|---|---|
| Nucleotide Accession | NP_061830.3 |
Application
SH3BP1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SH3BP1 antibody detected the SH3BP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
