SH3BP4 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SH3BP4 antibody detected the SH3BP4 protein (arrow).
SH3BP4; BOG25; EHB10; TTP; SH3 domain-binding protein 4; EH-binding protein 10; Transferrin receptor-trafficking protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
BOG25 EHB10 TTP
Alternative Names
SH3BP4 BOG25 EHB10 TTP SH3 domain-binding protein 4 EH-binding protein 10 Transferrin receptor-trafficking protein
Molecular Weight(MW)
107496 Da
Function
Functions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis
Tissue Specificity
Expressed in all tissues tested with higher expression in pancreas. Expressed by retinal pigment epithelial cells (at protein level)
Cellular Localization
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus (Probable) Note=Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus
SH3BP4 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SH3BP4 antibody detected the SH3BP4 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.