SHANK2 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the SHANK2 antibody detected the SHANK2 protein (arrow).
SHANK2; CORTBP1; KIAA1022; PROSAP1; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; Proline-rich synapse-associated protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CORTBP1 KIAA1022 PROSAP1
Alternative Names
SHANK2 CORTBP1 KIAA1022 PROSAP1 SH3 and multiple ankyrin repeat domains protein 2 Cortactin-binding protein 1 Proline-rich synapse-associated protein 1
Molecular Weight(MW)
158822 Da
Function
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction
Tissue Specificity
Isoform 3 is present in epithelial colonic cells (at protein level)
Cellular Localization
Cytoplasm (By similarity). Cell junction, synapse (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Cytoplasm, postsynaptic density of neuronal cells (By similarity)
SHANK2 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the SHANK2 antibody detected the SHANK2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.