Application
SHOC2 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow).Application
SHOC2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow).| Product Name | SHOC2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0862 |
|---|---|
| Alternative Names | SHOC2 KIAA0862 Leucine-rich repeat protein SHOC-2 Protein soc-2 homolog Protein sur-8 homolog |
| Molecular Weight(MW) | 64888 Da |
| Function | Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes |
| Tissue Specificity | This SHOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human SHOC2. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation |
| Entrez Gene | 8036 |
|---|---|
| Nucleotide Accession | NP_031399.2 |
Application
SHOC2 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow).
Application
SHOC2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
