ST3GAL6 SIAT10 Type 2 lactosamine alpha-2 3-sialyltransferase CMP-NeuAc:beta-galactoside alpha-2 3-sialyltransferase VI ST3Gal VI Sialyltransferase 10
Molecular Weight(MW)
38214 Da
Function
Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1
Tissue Specificity
Ubiquitous.
Cellular Localization
Golgi apparatus membrane; Single-pass type II membrane protein (Potential)
Western blot analysis of SIA10 Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).SIA10 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.