Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.Application
The anti-Siglec6 C-term Pab is used in Western blot to detect Siglec6 in mouse spleen tissue lysate.Application
SIGLEC6 Antibody western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SIGLEC6 antibody detected the SIGLEC6 protein (arrow).| Product Name | SIGLEC6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIGLEC6; CD33L; CD33L1; OBBP1; Sialic acid-binding Ig-like lectin 6; CD33 antigen-like 1; CDw327; Obesity-binding protein 1; CD_antigen=CD327; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD33L CD33L1 OBBP1 |
|---|---|
| Alternative Names | SIGLEC6 CD33L CD33L1 OBBP1 Sialic acid-binding Ig-like lectin 6 CD33 antigen-like 1 CDw327 Obesity-binding protein 1 CD_antigen=CD327 Flags: Precursor |
| Molecular Weight(MW) | 49913 Da |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface |
| Tissue Specificity | Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein |
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application
The anti-Siglec6 C-term Pab is used in Western blot to detect Siglec6 in mouse spleen tissue lysate.
Application
SIGLEC6 Antibody western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SIGLEC6 antibody detected the SIGLEC6 protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
