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SiglecL1 Antibody (C-term)

Catalog Number:OM221074
OM221074
Discount Price
OM221074-100ul
1~2 Week
100ul
OM221074-50ul
50ul
OM221074-20ul
20ul
1~2 Week
Product Profile
Product Name SiglecL1 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms SIGLECL1, SLG
Alternative Names SIGLEC12
SIGLECL1
SLG
Sialic acid-binding Ig-like lectin 12
Sialic acid-binding Ig-like lectin-like 1
Molecular Weight(MW) 64984 Da
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
Tissue Specificity Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 89858
Application

Application

The anti-SiglecL1 C-term Pab is used in Western blot to detect SiglecL1 in Jurkat cell lysate.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Application

SiglecL1 Antibody western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SiglecL1 antibody detected the SiglecL1 protein (arrow).
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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