Application
The anti-SIN3A Pab is used in Western blot to detect SIN3A in mouse kidney tissue lysate| Product Name | SIN3A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIN3A; Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SIN3A Paired amphipathic helix protein Sin3a Histone deacetylase complex subunit Sin3a Transcriptional corepressor Sin3a |
|---|---|
| Molecular Weight(MW) | 145175 Da |
| Function | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA (By similarity). Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation |
| Tissue Specificity | This SIN3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SIN3A. |
| Cellular Localization | Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L |
| Entrez Gene | 25942 |
|---|
Application
The anti-SIN3A Pab is used in Western blot to detect SIN3A in mouse kidney tissue lysate| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
