Application
SIPA1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SIPA1 antibody detected the SIPA1 protein (arrow).| Product Name | SIPA1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIPA1; SPA1; Signal-induced proliferation-associated protein 1; GTPase-activating protein Spa-1; p130 SPA-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SPA1 |
|---|---|
| Alternative Names | SIPA1 SPA1 Signal-induced proliferation-associated protein 1 GTPase-activating protein Spa-1 p130 SPA-1 |
| Molecular Weight(MW) | 112149 Da |
| Function | GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state |
| Tissue Specificity | Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord |
| Cellular Localization | Nucleus. Cytoplasm, perinuclear region. Endomembrane system; Peripheral membrane protein. Note=Mostly localized in the perinuclear membraneous region |
| Entrez Gene | 6494 |
|---|---|
| Nucleotide Accession | NP_006738.3 NP_694985.29 |
Application
SIPA1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SIPA1 antibody detected the SIPA1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
