Application
SIT1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SIT1 antibody detected the SIT1 protein (arrow).| Product Name | SIT1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SIT |
|---|---|
| Alternative Names | SIT1 SIT Signaling threshold-regulating transmembrane adapter 1 SHP2-interacting transmembrane adapter protein Suppression-inducing transmembrane adapter 1 gp30/40 |
| Molecular Weight(MW) | 21126 Da |
| Function | Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells. Involved in positive selection of T-cells |
| Tissue Specificity | Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 27240 |
|---|---|
| Nucleotide Accession | NP_055265.1 |
Application
SIT1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SIT1 antibody detected the SIT1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
