Application
Confocal immunofluorescent analysis of SLC11A2 Antibody (Center) (Cat#AP13801c) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
SLC11A2 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the SLC11A2 antibody detected the SLC11A2 protein (arrow).| Product Name | SLC11A2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IFWB |
| IF:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DCT1, DMT1, NRAMP2 |
|---|---|
| Alternative Names | SLC11A2 DCT1 DMT1 NRAMP2 Natural resistance-associated macrophage protein 2 Divalent cation transporter 1 Divalent metal transporter 1 |
| Molecular Weight(MW) | 62266 Da |
| Function | Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution |
| Tissue Specificity | Ubiquitously expressed. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in spleen, thymus and pancreas. Isoform 3 and isoform 4 are abundantly expressed in duodenum and kidney |
| Cellular Localization | Endosome membrane; Multi-pass membrane protein |
| Entrez Gene | 4891 |
|---|---|
| Nucleotide Accession | NP_001167598.1 NP_000608.1 |
Application
Confocal immunofluorescent analysis of SLC11A2 Antibody (Center) (Cat#AP13801c) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
SLC11A2 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the SLC11A2 antibody detected the SLC11A2 protein (arrow).| Application Notes | IF:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
