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SLC12A5 Antibody (N-term)

Catalog Number:OM221158
OM221158
Discount Price
OM221158-100ul
1~2 Week
100ul
OM221158-50ul
50ul
OM221158-20ul
20ul
1~2 Week
Product Profile
Product Name SLC12A5 Antibody (N-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KCC2, KIAA1176
Alternative Names SLC12A5
KCC2
KIAA1176
Solute carrier family 12 member 5
Electroneutral potassium-chloride cotransporter 2
K-Cl cotransporter 2
Neuronal K-Cl cotransporter
Molecular Weight(MW) 126184 Da
Function Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons
Tissue Specificity Brain specific. Detected in neuronal cells.
Cellular Localization Membrane; Multi-pass membrane protein.
Database Links
Entrez Gene 57468
Nucleotide Accession NP_065759.1 NP_001128243.1
Application

Application

SLC12A5 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC12A5 antibody detected the SLC12A5 protein (arrow).

Application

SLC12A5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC12A5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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