Application
SLC12A6 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SLC12A6 antibody detected the SLC12A6 protein (arrow).Application
SLC12A6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC12A6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SLC12A6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KCC3 |
|---|---|
| Alternative Names | SLC12A6 KCC3 Solute carrier family 12 member 6 Electroneutral potassium-chloride cotransporter 3 K-Cl cotransporter 3 |
| Molecular Weight(MW) | 127617 Da |
| Function | Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells |
| Tissue Specificity | Highly expressed in heart, brain and kidney. Detected at lower levels in skeletal muscle, placenta, lung and pancreas. Detected in umbilical vein endothelial cells. Isoform 2 is more abundant in kidney. Isoform 5 is testis specific Expressed in the proximal tubule of the kidney (at protein level) |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 9990 |
|---|---|
| Nucleotide Accession | NP_598408.1 NP_005126.1 |
Application
SLC12A6 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SLC12A6 antibody detected the SLC12A6 protein (arrow).
Application
SLC12A6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC12A6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
