Application
SLC12A7 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC12A7 antibody detected the SLC12A7 protein (arrow).Application
SLC12A7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC12A7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SLC12A7 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KCC4 |
|---|---|
| Alternative Names | SLC12A7 KCC4 Solute carrier family 12 member 7 Electroneutral potassium-chloride cotransporter 4 K-Cl cotransporter 4 |
| Molecular Weight(MW) | 119106 Da |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity) |
| Tissue Specificity | Detected in muscle, brain, lung, heart and kidney |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 10723 |
|---|---|
| Nucleotide Accession | NP_006589.2 |
Application
SLC12A7 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC12A7 antibody detected the SLC12A7 protein (arrow).
Application
SLC12A7 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC12A7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
