Application
SLC22A16 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLC22A16 antibody detected the SLC22A16 protein (arrow).| Product Name | SLC22A16 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OCT6 |
|---|---|
| Alternative Names | SLC22A16 OCT6 Solute carrier family 22 member 16 Carnitine transporter 2 Fly-like putative transporter 2 Organic cation transporter OKB1 Organic cation/carnitine transporter 6 |
| Molecular Weight(MW) | 64614 Da |
| Function | High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent |
| Tissue Specificity | Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase |
| Cellular Localization | Membrane; Multi-pass membrane protein (Potential). Cell membrane. Note=Detected in the plasma mebrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis |
| Entrez Gene | 85413 |
|---|---|
| Nucleotide Accession | NP_149116.2 |
Application
SLC22A16 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLC22A16 antibody detected the SLC22A16 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
