Application
SLC22A4 Antibody (C-term) western blot analysis in Hela(lane 1),K562(lane 2) cell line lysates (35ug/lane).This demonstrates the SLC22A4 antibody detected the SLC22A4 protein (arrow).| Product Name | SLC22A4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ETT, OCTN1, UT2H |
|---|---|
| Alternative Names | SLC22A4 ETT OCTN1 UT2H Solute carrier family 22 member 4 Ergothioneine transporter Organic cation/carnitine transporter 1 |
| Molecular Weight(MW) | 62155 Da |
| Function | Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET) |
| Tissue Specificity | Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 6583 |
|---|---|
| Nucleotide Accession | NP_003050.2 |
Application
SLC22A4 Antibody (C-term) western blot analysis in Hela(lane 1),K562(lane 2) cell line lysates (35ug/lane).This demonstrates the SLC22A4 antibody detected the SLC22A4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
