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SLC22A5 Antibody (C-term)

Catalog Number:OM221212
OM221212
Discount Price
OM221212-100ul
1~2 Week
100ul
OM221212-50ul
50ul
OM221212-20ul
20ul
1~2 Week
Product Profile
Product Name SLC22A5 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms OCTN2
Alternative Names SLC22A5
OCTN2
Solute carrier family 22 member 5
High-affinity sodium-dependent carnitine cotransporter
Organic cation/carnitine transporter 2
Molecular Weight(MW) 62752 Da
Function Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3
Tissue Specificity Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells
Cellular Localization Membrane; Multi-pass membrane protein.
Database Links
Entrez Gene 6584
Nucleotide Accession NP_003051.1
Application

Application

SLC22A5 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SLC22A5 antibody detected the SLC22A5 protein (arrow).

Application

SLC22A5 Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC22A5 Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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