Application
SLC24A1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC24A1 antibody detected the SLC24A1 protein (arrow).| Product Name | SLC24A1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0702, NCKX1 |
|---|---|
| Alternative Names | SLC24A1 KIAA0702 NCKX1 Sodium/potassium/calcium exchanger 1 Na(+)/K(+)/Ca(2+)-exchange protein 1 Retinal rod Na-Ca+K exchanger |
| Molecular Weight(MW) | 121374 Da |
| Function | Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) |
| Tissue Specificity | Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 9187 |
|---|---|
| Nucleotide Accession | NP_004718.1 |
Application
SLC24A1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC24A1 antibody detected the SLC24A1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
