Application
SLC27A1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC27A1 antibody detected the SLC27A1 protein (arrow).| Product Name | SLC27A1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC27A1; ACSVL5; FATP1; Long-chain fatty acid transport protein 1; Solute carrier family 27 member 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ACSVL5 FATP1 |
|---|---|
| Alternative Names | SLC27A1 ACSVL5 FATP1 Long-chain fatty acid transport protein 1 Solute carrier family 27 member 1 |
| Molecular Weight(MW) | 71108 Da |
| Function | Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity) |
| Tissue Specificity | Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver |
| Cellular Localization | Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm (By similarity). Note=Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes (By similarity) |
| Entrez Gene | 376497 |
|---|---|
| Nucleotide Accession | NP_940982.1 |
Application
SLC27A1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC27A1 antibody detected the SLC27A1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
