Application
SLC7A7 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SLC7A7 antibody detected the SLC7A7 protein (arrow).| Product Name | SLC7A7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC7A7; Y+L amino acid transporter 1; Monocyte amino acid permease 2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SLC7A7 Y+L amino acid transporter 1 Monocyte amino acid permease 2 Solute carrier family 7 member 7 y(+)L-type amino acid transporter 1 |
|---|---|
| Molecular Weight(MW) | 55991 Da |
| Function | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L- arginine in monocytes |
| Tissue Specificity | Highest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein |
| Entrez Gene | 9056 |
|---|---|
| Nucleotide Accession | NP_003973.3 NP_001119577.1 NP_001119578.1 |
Application
SLC7A7 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SLC7A7 antibody detected the SLC7A7 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
