SLC9A3R2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC9A3R2 antibody detected the SLC9A3R2 protein (arrow).
SLC9A3R2; NHERF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 isoform A3 regulatory factor 2; Tyrosine kinase ac
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
NHERF2
Alternative Names
SLC9A3R2 NHERF2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 NHE3 kinase A regulatory protein E3KARP SRY-interacting protein 1 Sodium-hydrogen exchanger regulatory factor 2 Solute carrier family 9 isoform A3 regulatory factor 2 Tyrosine kinase ac
Molecular Weight(MW)
37414 Da
Function
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus
Tissue Specificity
Widely expressed.
Cellular Localization
Endomembrane system; Peripheral membrane protein. Nucleus. Apical cell membrane (By similarity) Note=Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern
SLC9A3R2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SLC9A3R2 antibody detected the SLC9A3R2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.