SLCO1C1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SLCO1C1 antibody detected the SLCO1C1 protein (arrow).
SLCO1C1; OATP14; OATP1C1; OATPF; SLC21A14; Solute carrier organic anion transporter family member 1C1; Organic anion transporter F; Organic anion transporter polypeptide-related protein 5; Organic anion-transporting polypeptide 14; Solute carrier family 21
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
OATP14 OATP1C1 OATPF SLC21A14
Alternative Names
SLCO1C1 OATP14 OATP1C1 OATPF SLC21A14 Solute carrier organic anion transporter family member 1C1 Organic anion transporter F Organic anion transporter polypeptide-related protein 5 Organic anion-transporting polypeptide 14 Solute carrier family 21
Molecular Weight(MW)
78696 Da
Function
Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain (By similarity)
Tissue Specificity
Highly expressed in brain and in Leydig cells in testis. Detected in many brain regions with the exception of pons and cerebellum. Not strongly enriched in cerebral microvessels
Cellular Localization
Cell membrane; Multi-pass membrane protein. Note=Expressed in both luminal and abluminal membranes of brain capillary endothelial cells. Localized to the apical membrane and basal surfaces of choroid plexus (By similarity)
SLCO1C1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SLCO1C1 antibody detected the SLCO1C1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.