Application
SLCO3A1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SLCO3A1 antibody detected the SLCO3A1 protein (arrow).| Product Name | SLCO3A1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLCO3A1; OATP3A1; OATPD; SLC21A11; Solute carrier organic anion transporter family member 3A1; Organic anion transporter polypeptide-related protein 3; Organic anion-transporting polypeptide D; PGE1 transporter; Sodium-independent organic anion transporter |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OATP3A1 OATPD SLC21A11 |
|---|---|
| Alternative Names | SLCO3A1 OATP3A1 OATPD SLC21A11 Solute carrier organic anion transporter family member 3A1 Organic anion transporter polypeptide-related protein 3 Organic anion-transporting polypeptide D PGE1 transporter Sodium-independent organic anion transporter |
| Molecular Weight(MW) | 76553 Da |
| Function | Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate (PubMed:10873595). Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS (PubMed:16971491) |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages and absent from Sertoli cells, while isoform 2 is present in both (at protein level). Expressed in the choroid plexus epithelium, isoform 1 being localized at the basolateral membrane and isoform 2 at the apical one, as well as in the subapical intracellular vesicular compartments. Differential expression of both isoforms is also observed in other brain region: isoform 1 is very abundant in the gray matter of the frontal cortex, but is not associated with neuronal cell bodies Not detected in the white matter. In contrast, isoform 2 is associated with neuronal bodies and axons in both the gray and the white matters of the frontal cortex |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 28232 |
|---|---|
| Nucleotide Accession | NP_037404.2 NP_001138516.1 |
Application
SLCO3A1 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SLCO3A1 antibody detected the SLCO3A1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
