Application
SLU7 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SLU7 Antibody detected the SLU7 protein (arrow).| Product Name | SLU7 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLU7; Pre-mRNA-splicing factor SLU7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SLU7 Pre-mRNA-splicing factor SLU7 |
|---|---|
| Molecular Weight(MW) | 68387 Da |
| Function | Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation |
| Tissue Specificity | This SLU7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the N-terminal region of human SLU7. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules |
| Entrez Gene | 10569 |
|---|---|
| Nucleotide Accession | NP_006416.3 |
Application
SLU7 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SLU7 Antibody detected the SLU7 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
