Application
SMAD1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SMAD1 antibody detected the SMAD1 protein (arrow).| Product Name | SMAD1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; Transforming growth factor-beta-signaling protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BSP1 MADH1 MADR1 |
|---|---|
| Alternative Names | SMAD1 BSP1 MADH1 MADR1 Mothers against decapentaplegic homolog 1 JV4-1 Mad-related protein 1 SMAD family member 1 Transforming growth factor-beta-signaling protein 1 |
| Molecular Weight(MW) | 52260 Da |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 |
| Tissue Specificity | Ubiquitous. Highest expression seen in the heart and skeletal muscle |
| Cellular Localization | Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane |
| Entrez Gene | 4086 |
|---|---|
| Nucleotide Accession | NP_005891.1 |
Application
SMAD1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SMAD1 antibody detected the SMAD1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
