Application
SMG5 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SMG5 antibody detected the SMG5 protein (arrow).| Product Name | SMG5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMG5; EST1B; KIAA1089; Protein SMG5; EST1-like protein B; LPTS-RP1; LPTS-interacting protein; SMG-5 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EST1B KIAA1089 |
|---|---|
| Alternative Names | SMG5 EST1B KIAA1089 Protein SMG5 EST1-like protein B LPTS-RP1 LPTS-interacting protein SMG-5 homolog |
| Molecular Weight(MW) | 113928 Da |
| Function | Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1 Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm Detected in cytoplasmic mRNA decay bodies |
| Entrez Gene | 23381 |
|---|---|
| Nucleotide Accession | NP_056142.2 |
Application
SMG5 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SMG5 antibody detected the SMG5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
