Application
SMN1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SMN1 antibody detected the SMN1 protein (arrow).| Product Name | SMN1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMN1; SMN; SMNT; Survival motor neuron protein; Component of gems 1; Gemin-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SMN SMNT |
|---|---|
| Alternative Names | SMN1 SMN SMNT Survival motor neuron protein Component of gems 1 Gemin-1 |
| Molecular Weight(MW) | 31849 Da |
| Function | The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs |
| Tissue Specificity | Expressed in a wide variety of tissues. Expressed at high levels in brain, kidney and liver, moderate levels in skeletal and cardiac muscle, and low levels in fibroblasts and lymphocytes. Also seen at high levels in spinal cord. Present in osteoclasts and mononuclear cells (at protein level) |
| Cellular Localization | Cytoplasm. Nucleus, gem. Note=Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems) |
| Entrez Gene | 6607 |
|---|---|
| Nucleotide Accession | NP_000335.1 |
Application
SMN1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SMN1 antibody detected the SMN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
