Application
SMO Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SMO antibody detected the SMO protein (arrow).| Product Name | SMO Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMO; SMOH; Smoothened homolog; Protein Gx |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SMOH |
|---|---|
| Alternative Names | SMO SMOH Smoothened homolog Protein Gx |
| Molecular Weight(MW) | 86397 Da |
| Function | G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia |
| Tissue Specificity | This SMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-567 amino acids from the Central region of human SMO. |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 6608 |
|---|---|
| Nucleotide Accession | NP_005622.1 |
Application
SMO Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SMO antibody detected the SMO protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
