Application
A. Western blot analysis on fetal brain lysate using anti-beta synuclein RabMAb (Cat. #AJ1096a), dilution 1:10,000.Application
B. Immunohistochemical staining of paraffin-embedded human brain using anti-Beta-Synuclein RabMAb (Cat. #AJ1096a).Application
C. Immunofluorescent staining of PC12 cells using anti-Beta-Synuclein RabMAb (Cat. #AJ1096a).| Product Name | SNCB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNCB, Beta-synuclein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1537Y |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SNCB Beta-synuclein |
|---|---|
| Molecular Weight(MW) | 14288 Da |
| Function | Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53- dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease |
| Tissue Specificity | Expressed predominantly in brain; concentrated in presynaptic nerve terminals |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 6620 |
|---|
Application
A. Western blot analysis on fetal brain lysate using anti-beta synuclein RabMAb (Cat. #AJ1096a), dilution 1:10,000.
Application
B. Immunohistochemical staining of paraffin-embedded human brain using anti-Beta-Synuclein RabMAb (Cat. #AJ1096a).
Application
C. Immunofluorescent staining of PC12 cells using anti-Beta-Synuclein RabMAb (Cat. #AJ1096a).| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
