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SNRPC Antibody (C-term)

Catalog Number:OM221616
OM221616
Discount Price
OM221616-100ul
1~2 Week
100ul
OM221616-50ul
50ul
OM221616-20ul
20ul
1~2 Week
Product Profile
Product Name SNRPC Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias SNRPC; U1 small nuclear ribonucleoprotein C
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names SNRPC
U1 small nuclear ribonucleoprotein C
Molecular Weight(MW) 17394 Da
Function Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region
Tissue Specificity This SNRPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130~159 amino acids from the C-terminal region of human SNRPC.
Cellular Localization Nucleus.
Database Links
Entrez Gene 6631
Application

Application

Western blot analysis of anti-SNRPC Antibody (C-term) in K562 cell line lysates (35ug/lane). SNRPC(arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with PSMA6 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

SNRPC Antibody (C-term) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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