SNX5 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SNX5 antibody detected the SNX5 protein (arrow).
May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation
Tissue Specificity
This SNX5 Antibody Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-term region of human SNX5.
Cellular Localization
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle Note=Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2). Detected on macropinosomes. Targeted to membrane ruffles in response to EGFR stimulation
SNX5 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SNX5 antibody detected the SNX5 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.