Application
Western blot analysis of SNX6 Antibody (N-term) (Cat# AP1464a) in HepG2 cell line lysates (35ug/lane). SNX6 (arrow) was detected using the purified Pab (1:60 dilution).| Product Name | SNX6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNX6; Sorting nexin-6; TRAF4-associated factor 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SNX6 Sorting nexin-6 TRAF4-associated factor 2 |
|---|---|
| Molecular Weight(MW) | 46649 Da |
| Function | May be involved in several stages of intracellular trafficking. Promotes lysosomal degradation of CDKN1B (By similarity). Plays a role in retrograde protein transport from endosomes to the trans-Golgi network. May function as link between transport vesicles and dynactin. Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network. May contribute to transcription regulation |
| Tissue Specificity | This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88~118 amino acids from the N-terminal region of human SNX6. |
| Cellular Localization | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus Note=Interaction with SNX1 or SNX2 promotes location at endosome membranes. Only a minor proportion is seen in the nucleus |
| Entrez Gene | 58533 |
|---|
Application
Western blot analysis of SNX6 Antibody (N-term) (Cat# AP1464a) in HepG2 cell line lysates (35ug/lane). SNX6 (arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
