Application
SOCS6 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SOCS6 antibody detected the SOCS6 protein (arrow).Application
SOCS6 Antibody (N-term) (AP14118a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SOCS6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SOCS6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOCS6; CIS4; SOCS4; Suppressor of cytokine signaling 6; Cytokine-inducible SH2 protein 4; Suppressor of cytokine signaling 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CIS4 SOCS4 |
|---|---|
| Alternative Names | SOCS6 CIS4 SOCS4 Suppressor of cytokine signaling 6 Cytokine-inducible SH2 protein 4 Suppressor of cytokine signaling 4 |
| Molecular Weight(MW) | 59528 Da |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor |
| Tissue Specificity | This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-69 amino acids from the N-terminal region of human SOCS6. |
| Entrez Gene | 9306 |
|---|---|
| Nucleotide Accession | NP_004223.2 |
Application
SOCS6 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SOCS6 antibody detected the SOCS6 protein (arrow).
Application
SOCS6 Antibody (N-term) (AP14118a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SOCS6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
