The protein encoded by this gene contains a SH2 domain and
a SOCS BOX domain. The protein thus belongs to the suppressor of
cytokine signaling (SOCS), also known as STAT-induced STAT
inhibitor (SSI), protein family. SOCS family members are known to
be cytokine-inducible negative regulators of cytokine signaling.
Two alternatively spliced transcript variants encoding the same
protein have been found for this gene.1) Hu, G., et al. J. Infect. Dis. 202(1):125-135(2010)
Immunogen
This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human SOCS4.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.