Application
SOST Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SOST antibody detected the SOST protein (arrow).| Product Name | SOST Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOST; Sclerostin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SOST Sclerostin |
|---|---|
| Molecular Weight(MW) | 24031 Da |
| Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation |
| Tissue Specificity | Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level) |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 50964 |
|---|---|
| Nucleotide Accession | NP_079513.1 |
Application
SOST Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SOST antibody detected the SOST protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
