Application
Western blot analysis on NCCIT cell lysate using anti-SOX2 RabMAb (Cat. #AJ1732b).Application
Immunohistochemical analysis of paraffin-embedded fetal brain tissue using anti-SOX2 RabMAb (Cat. #AJ1732b).Application
Immunohistochemical analysis of paraffin-embedded glioma using anti-SOX2 RabMAb (Cat. #AJ1732b).Application
Immunohistochemical analysis of paraffin-embedded normal brain tissue using anti-SOX2 RabMAb (Cat. #AJ1732b).| Product Name | SOX2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3130 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 34310 Da |
|---|---|
| Function | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity) |
| Tissue Specificity | A synthetic peptide corresponding to residues in human SOX2 was used as an immunogen. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6657 |
|---|
Application
Western blot analysis on NCCIT cell lysate using anti-SOX2 RabMAb (Cat. #AJ1732b).
Application
Immunohistochemical analysis of paraffin-embedded fetal brain tissue using anti-SOX2 RabMAb (Cat. #AJ1732b).
Application
Immunohistochemical analysis of paraffin-embedded glioma using anti-SOX2 RabMAb (Cat. #AJ1732b).
Application
Immunohistochemical analysis of paraffin-embedded normal brain tissue using anti-SOX2 RabMAb (Cat. #AJ1732b).| Application Notes | WB:1:500~1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
