Application
SOX3 Antibody (Center) western blot analysis in MDA-MB453,HL-60 cell line lysates (35ug/lane).This demonstrates the SOX3 antibody detected the SOX3 protein (arrow).| Product Name | SOX3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOX3; Transcription factor SOX-3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SOX3 Transcription factor SOX-3 |
|---|---|
| Molecular Weight(MW) | 45210 Da |
| Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity) |
| Tissue Specificity | This SOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-204 amino acids from the Central region of human SOX3. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6658 |
|---|---|
| Nucleotide Accession | NP_005625.2 |
Application
SOX3 Antibody (Center) western blot analysis in MDA-MB453,HL-60 cell line lysates (35ug/lane).This demonstrates the SOX3 antibody detected the SOX3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
