Application
Sox2-pS246-pS249-pS250--pS251 Antibody western blot analysis in 293,CEM cell line lysates (15ug/lane).This demonstrates the Sox2 antibody detected the Sox2 protein (arrow).| Product Name | Sox2-pS246-pS249-pS250--pS251 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOX2; Transcription factor SOX-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SOX2 Transcription factor SOX-2 |
|---|---|
| Molecular Weight(MW) | 34310 Da |
| Function | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity) |
| Tissue Specificity | This Sox2-pS246-pS249-pS250--pS251 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-260 amino acids from the C-terminal region of human Sox2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6657 |
|---|---|
| Nucleotide Accession | NP_003097.1 |
Application
Sox2-pS246-pS249-pS250--pS251 Antibody western blot analysis in 293,CEM cell line lysates (15ug/lane).This demonstrates the Sox2 antibody detected the Sox2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
