Application
SP3 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SP3 antibody detected the SP3 protein (arrow).| Product Name | SP3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SP3; Transcription factor Sp3; SPR-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SP3 Transcription factor Sp3 SPR-2 |
|---|---|
| Molecular Weight(MW) | 81925 Da |
| Function | Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone- induction and house-keeping |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Nucleus. Nucleus, PML body. Note=Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies |
| Entrez Gene | 6670 |
|---|---|
| Nucleotide Accession | NP_003102.1 NP_001166183.1 |
Application
SP3 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SP3 antibody detected the SP3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
