Application
SPDYC Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SPDYC antibody detected the SPDYC protein (arrow).| Product Name | SPDYC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPDYC; Speedy protein C; Rapid inducer of G2/M progression in oocytes C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SPDYC Speedy protein C Rapid inducer of G2/M progression in oocytes C |
|---|---|
| Molecular Weight(MW) | 33166 Da |
| Function | Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase |
| Tissue Specificity | Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis |
| Cellular Localization | Cytoplasm. Note=Colocalizes with tubulin gamma during interphase. During mitosis, enriched at the spindle poles and the midbody during telophase |
| Entrez Gene | 387778 |
|---|---|
| Nucleotide Accession | NP_001008778.1 |
Application
SPDYC Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SPDYC antibody detected the SPDYC protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
