Application
SPIRE2 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SPIRE2 antibody detected the SPIRE2 protein (arrow).| Product Name | SPIRE2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SPIRE2; KIAA1832; SPIR2; Protein spire homolog 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1832 SPIR2 |
|---|---|
| Alternative Names | SPIRE2 KIAA1832 SPIR2 Protein spire homolog 2 |
| Molecular Weight(MW) | 79671 Da |
| Function | Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis |
| Tissue Specificity | This SPIRE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the Central region of human SPIRE2. |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cytosol (By similarity). Cytoplasm, perinuclear region (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) Note=Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion (By similarity) |
| Entrez Gene | 84501 |
|---|---|
| Nucleotide Accession | NP_115827.1 |
Application
SPIRE2 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SPIRE2 antibody detected the SPIRE2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
